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Physical component Quality of life (QOL) reflects the impact of time and moderate chronic kidney disease, unlike SF-6D utility and mental component SF-36 QOL: An AUSDiab analysis

Nephrology Jul 27, 2018

Wong MG, et al. - Researchers used a community cohort of people with and without chronic kidney disease (CKD) markers at baseline, to assess change in commonly-used measures of QOL over the passage of five years. Based on the baseline presence of reduced eGFR or albuminuria in 6400 participants in the AusDiab surveys, regression analyses were performed to compare the changes in SF-6D utility, and SF-36 Physical (PCS) and Mental (MCS) Component Summary scores. Observations over 5 years revealed no impact of time or markers of CKD health on utility and mental QOL; these appeared stable during this time period. Physical QOL was recognized as a more likely candidate assessment measure for intervention and health service evaluations because it appeared to deteriorate with time, especially for those with CKD.
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