Levy ME, et al. - Researchers examined how mood, anxiety, stress-/trauma-related, and psychotic disorders, both treated and untreated, influence the duration of unsuppressed HIV viral load (VL) in people living with HIV (PLWH). For this purpose, they analyzed data in the DC Cohort—an observational clinical cohort of PLWH followed from 2011 to 2018 at 14 sites in Washington, DC—which consisted of 5,904 participants (median age 51; 70% men; 82% Black). Of these, 45% had ≥ 1 psychiatric disorder; these included 38% with mood disorders (50% treated), 18% with anxiety or stress-/trauma-related disorders (64% treated), and 4% with psychotic disorders (52% treated). More time with unsuppressed VL was observed among PLWH with depressive and bipolar disorders, particularly when untreated, than PLWH without a mood disorder. Findings suggested the possible value of treating mood disorders for promoting sustained viral suppression.