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Peripapillary border tissue of the choroid and peripapillary scleral flange in human eyes

Acta Ophthalmologica Aug 23, 2019

Jonas RA, et al. - In this investigation involving 85 eyes (85 patients) with an age of 62.0 years (14.1 years), researchers evaluated dimensions and connections of the peripapillary border tissue of the choroid (PBT-C) and peripapillary scleral flange (PBT-S). The histomorphometric investigation involved histological sections of enucleated eyes of Caucasian patients. The PBT dimensions were measured using light microscopy. The thicker thickness of PBT-S (mean:83 μm (21 μm)) was associated with the presence of glaucoma. Optic nerve pia mater thickness (mean:109 μm (44 μm)) increased with the presence of glaucoma, but not the axial length. According to findings, peripapillary border tissue of the choroid (PBT-C) and PBT-S as a continuation of the optic nerve pia mater are separate structures, with PBT-C remodelling during myopic axial elongation and PBT-S being largely autonomous of axial elongation. For optic nerve head biomechanics, PBT-C and PBT-S may be important for separating the choroidal space from the intrapapillary compartment.
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