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Perioperative subconjunctival triamcinolone acetonide injection for prevention of inflammation and macular oedema after cataract surgery

Acta Ophthalmologica Jun 23, 2019

Lindholm JM, et al. - In this prospective non-randomized controlled clinical trial, researchers compared the effectiveness, safety and tolerability of a single perioperative subconjunctival injection of triamcinolone acetonide (TA) with steroid drops for the prevention of macular oedema and ocular inflammation after cataract surgery. They analyzed 101 eyes of 101 patients having elective cataract surgery at Kymenlaakso Central Hospital, Kotka, Finland. For this investigation, 50 eyes received conventional postoperative care with dexamethasone 1 mg/ml eye drops (DEX), and 51 eyes received a perioperative 20 mg subconjunctival injection of TA. After cataract surgery, perioperative subconjunctival TA was effective in preventing ocular inflammation and macular oedema. In modern cataract surgery, subconjunctival TA combined with intracameral cefuroxime provides a remarkable option for dropless postoperative care. There have been no serious adverse events observed.
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