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Perioperative opioid prescriptions associated with stress incontinence and pelvic organ prolapse surgery

American Journal of Obstetrics and Gynecology Aug 24, 2020

Willis-Gray MG, Young JC, Pate V, et al. - Among women who underwent stress urinary incontinence and pelvic organ prolapse surgeries, the proportion who filled perioperative opioid prescriptions was determined. Further, comparison was performed of factors linked with these opioid prescriptions. Using a population-based cohort of commercially insured individuals in the 2005–2015 IBM MarketScan databases, Researchers identified 217,460 opioid-naive women who underwent urogynecologic surgery; of these, 61,025 (28.1%) had pelvic organ prolapse and stress urinary incontinence surgeries, 85,575 (39.4%) had stress urinary incontinence surgery without pelvic organ prolapse surgery, and 70,860 (32.6%) had pelvic organ prolapse surgery without stress urinary incontinence surgery. A perioperative opioid prescription with the median quantity of 30 pills was filled for 167,354 (77.0%) women. An opioid prescription was filled within 90 to 180 days after surgery for prolonged use in 7.5% (95% confidence interval, 7.3–7.6), however, significantly lower rates of continuously filled opioid prescriptions were noted at 0.06% (95% confidence interval, 0.05–0.08) at 180 days and 0.04% (95% confidence interval, 0.02–0.05) at 1 year after surgery.

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