Zorrilla-Vaca A, et al. - Whether intraoperative or postoperative infusion of dextrose could prevent postoperative nausea and vomiting was investigated in this meta-analysis of 10 randomized controlled trials involving 987 patients. Researchers included studies comparing the use of a perioperative dextrose infusion (n = 465) to control (n = 522). These trials were identified from PubMed, Embase, Cochrane library, and Google Scholar. In the postanesthesia care unit or within the first 24 h of operation, a significant decrease in postoperative nausea and vomiting was not evident in relation to perioperative dextrose infusion. Although a significant decrease in antiemetic treatment within the first 24 h was noted in correlation with the use of dextrose, its use also raised postoperative plasma glucose levels vs controls. Overall, perioperative dextrose use did not lead to a statistically significant link with postoperative nausea and vomiting. When utilized, evaluation for postoperative hyperglycemia via plasma glucose monitoring is advised.