Gusdon AM, Nyquist PA, Torres-Lopez VM, et al. - In patients with cancer without central nervous system involvement, researchers described perihematomal edema (PHE) and hematoma volumes following spontaneous nontraumatic intracerebral hemorrhage (ICH). Through automated searches of institutional databases, patients with active malignancy who developed ICH were retrospectively identified. They identified control patients with ICH and without active cancer. Cancer patients (n = 80) and controls (n = 136) had similar demographics, although the prevalence of hypertension among controls was greater. Most cancer patients had recently received chemotherapy and had malignancy recurrence. The authors discovered that active cancer patients with ICH have increased the volume of PHE. PHE growth was independent of thrombocytopenia but related to blood product transfusion. Findings suggested an association of 30-day mortality with PHE and ICH volumes and blood product transfusion.