• Profile
Close

Peri-operative derangement in liver function tests in older patients with neck of femur fracture

Osteoporosis International Jan 21, 2021

Powell J, et al. - In elderly people with neck of femur (NOF) fracture, derangement in liver function tests (LFTs) has been frequently identified in the peri-operative period and is possibly indicative of serious and treatable underlying pathology as well as prognosis. On admission, underlying bone pathology such as osteomalacia or Paget’s disease may be suspected when raised alkaline phosphatase (ALP) levels with normal gamma-glutamyl transferase (GGT) are identified but these do not confirm or exclude osteoporosis. Non-bone pathology such as congestive cardiac failure and chronic kidney disease can also be suspected in cases with elevated ALP. In cardiac failure, LFT derangement is linked with poorer prognosis. Overall findings suggest that there is wide differential diagnosis for deranged LFTs in the elderly peri-operatively; however, careful history and examination can aid in eliciting most causes with occasional need for further investigations.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay