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Pentosidine concentration is associated with degenerative lumbar scoliosis in older women: Preliminary results

European Spine Journal Nov 15, 2017

Eguchi Y, et al. - The prevalence of sarcopenia in degenerative lumbar scoliosis (DLS) was determined in this study, along with the link between biochemical markers including major advanced glycation end products (AGEs), pentosidine, and DLS in older women. Findings revealed that sarcopenia was implicated in DLS, and high serum pentosidine levels were related to the severity of coronal and sagittal malalignment in older women. This revelation indicated that high levels of AGEs are a potential biomarker for the progression of lumbar scoliosis and kyphotic deformity.
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