Salcedo MP, Sood AK, Jhingran A, et al. - By prospectively examining women (n = 239) who received pelvic radiotherapy (RT) for cervical, endometrial, or vaginal cancer between 2008 and 2015, researchers intended to evaluate the incidence of pelvic fractures as well as alterations in bone mineral density (BMD) following pelvic RT. At the baseline and 3 months, 1 year, and 2 years following RT, BMD scans and biomarkers of bone turnover were collected. The evaluation of imaging studies was done for pelvic fractures for up to 5 years. The median age at diagnosis was 51 years, and menopausal patients were 132 (56%) in total. Findings revealed significant reductions in BMD in a high proportion of women following pelvic RT, with 7.8% diagnosed with a pelvic fracture. For these high-risk women, strongly considering BMD screening as well as pharmacologic intervention was recommended.