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Patient-reported outcomes from a phase 3 randomized controlled trial of inotuzumab ozogamicin vs standard therapy for relapsed/refractory acute lymphoblastic leukemia

Cancer Mar 16, 2018

Kantarjian HM, et al. - In the phase 3 randomized controlled INO-VATE trial, superior clinical activity of inotuzumab ozogamicin (InO), an anti-CD22 antibody-calicheamicin conjugate, was shown in comparison to standard-of-care (SOC) chemotherapies for relapsed/refractory B-cell acute lymphoblastic leukemia. Herein, patient-reported outcomes (PROs) from that study were evaluated. With the observed superior clinical efficacy and better quality of life (QoL), favorable benefit/risk ratio of InO for the treatment of relapsed/refractory acute lymphoblastic leukemia was supported by the current PRO data.
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