Jacquot C, et al. - Study's aim was to appraise parental versus non-parental–directed donation. As compared to the respective repeat donors, first-time non-parental and community donors had significantly higher infectious disease risk; first-time parental donors had the highest rates of positive infectious disease testing. These outcomes suggested that repeat community donors or first-time non-parental donors provided a safer alternative.

Methods

• From January 1997 through December 2008, blood-collection records were reviewed, including infectious disease results, among parental, non-parental, and community donations.
• Mann-Whitney U test compared infectious disease rates.

Results

• Analysts tested 1532 parental, 4910 non-parental, and 17,423 community donations.
• The median rate of positive infectious disease testing was 8.66% (interquartile range (IQR), 4.49%) for first-time donors and 1.26% (IQR, 5.86%) for repeat donors, among parental donors.
• Among non-parental donors, the rate was 1.09% (IQR, 0.98%) for first-time donors and 0% (IQR, 0.83%) for repeat donors.
• In addition, among community donors, the rate was 2.95% (IQR, 1.50%) for first-time donors and 0.45% (IQR, 0.82%) for repeat donors.
• Results reported significantly higher (7.63%) mean rate of positive infectious disease testing for first-time parental donors.
• On the other hand, all repeat donors had similar rates.
• In addition, the rate of positive infectious disease testing among first-time non-parental donors was significantly lower than that in the other groups, especially for the period from 2001 through 2008.