Onishi AC, et al. - In this retrospective cross-sectional study, researchers assessed parafoveal and peripapillary perfusion in healthy, glaucoma suspect, normal-tension glaucoma, and primary open-angle glaucoma patients. The study sample consisted of 56 subjects presenting to the Department of Ophthalmology of Northwestern University, Feinberg School of Medicine between April 2016 and January 2018. In primary open-angle glaucoma and normal-tension glaucoma, there were important decreases in parafoveal superficial vessel density but not suspect eyes relative to healthy eyes. Similarly, in primary open-angle and normal-tension glaucoma eyes, decreases were observed in parafoveal inner retinal thickness, but not suspect eyes compared with healthy controls. These findings provide additional evidence that these changes in glaucoma patients may be useful in diagnosing and monitoring the disease.