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Pain in long‐term survivors of childhood cancer: A systematic review of the current state of knowledge and a call to action from the Children's Oncology Group

Cancer Nov 03, 2020

Schulte FSM, Patton M, Alberts NM, et al. - Researchers conducted this study with the aim to report on: 1) the prevalence of pain in survivors of childhood cancer, 2) methods of pain measurement, 3) correlations between pain and biopsychosocial factors, and 4) recommendations for future research. From the PubMed, PsycINFO, EMBASE, and Web of Science databases, they identified 73 articles for inclusion in the final review. Items created by the authors for the purpose of the study (45.2%) or health‐related quality‐of‐life/health status questionnaires (42.5%) were the common measures of pain. Across studies, 4.3% to 75% of survivors reported presence of pain. Chronic pain was investigated in three studies according to the definition in the International Classification of Diseases. The findings indicated that the risk of experiencing pain was higher among survivors of childhood cancer vs controls. Fatigue was consistently linked with pain, females described more pain relative to males, and other factors related to pain will need stronger evidence.

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