Huang HY, et al. - Researchers estimated 66 non-cystic fibrosis (non-CF) bronchiectasis patients to analyze if desaturation during 6-min walk test (6MWT) could be a predictor for osteoporosis risk. They determined lung function, walking distance, the lowest oxygen saturation (SpO₂), the fall in SpO₂ (ΔSpO₂), and the distance-saturation product (DSP) during the 6MWT. They noticed osteoporosis prevalent in more desaturators (ie, ΔSpO₂ > 10% or the lowest SpO₂ < 88%) as compared to non-desaturators. A positive correlation was observed between bone mineral density (BMD) and the lowest SpO₂ whereas negatively associated with ΔSpO₂ and severe exacerbations. Old age, low body mass index, and severe exacerbation were also included as risk factors.