Outpatient pulmonary rehabilitation for severe asthma with fixed airway obstruction: Comparison with COPD
Journal of Asthma Feb 02, 2019
Bellocq A, et al. - Researchers performed this retrospective analysis to determine the impact of pulmonary rehabilitation (PR) in nonsmoking patients with severe asthma and airway obstruction vs sex-, age-, FEV1-, and BMI-matched COPD controls. This study included 29 patients, each with asthma and COPD. Participants had moderate airway obstruction. Asthma vs COPD patients had higher VO2 at peak. Findings revealed a significant and similar increase in constant work cycling test of 378 s and 377 s after PR in asthma and COPD groups. Similar changes were observed in Hospital Anxiety and Depression Scale (HAD) total score. In both groups, significantly improved quality of life was observed. Findings revealed the feasibility as well as the good tolerability of outpatient PR in patients with severe asthma with fixed airway obstruction. Strong improvements in HAD and St. George’s Respiratory Questionnaire scores, as well as constant work-rate sub-maximal cycling, were observed with a nondedicated program and similar amplitude as with COPD.
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