Stephenson ED, et al. - Authors ascertained the outcomes of open vs endoscopic skull base surgery in a cohort of patients 70 years or older. They also assessed if age, type of disease process, and approach (endoscopic vs traditional open surgery) are related to increased intraoperative and postoperative complications in this population. Out of 219 patients included in the study, 166 were aged 70.0 to 79.9 years and 53 patients were older than 80 years; 54.8% were men and 73.7% were white. In persons 70 years or older, skull base surgery is a safe option, with similar outcomes across age ranges, surgical approaches, and disease processes. Complications between patients aged 70.0 to 79.9 years vs those older than 80 years, endoscopic vs open surgery, or benign vs malignant neoplasms did not demonstrate any clinically meaningful difference. Intraoperative major bleeding, postoperative cerebrospinal fluid leak, or postoperative bleeding did not differ significantly between the endoscopic and open surgery groups.