Bayyoud T, Gelisken F, Rohrbach JM, et al. - In this retrospective study, researchers sought to better evaluate clinical trajectories of patients with or without ocular comorbidity after Descemet membrane endothelial keratoplasty. Three hundred sixty-one eyes separated into group 1 (n = 229; eyes with endothelial disease only) and group 2 (n = 132; eyes with additional ocular comorbid conditions like herpetic eye disease 18/132 (13.6%), glaucoma 16/132 (12.1%), dry age-related macular degeneration 14/132 (10.6%), epiretinal membranes 10/132 (7.6%), and wet age-related macular degeneration 9/132 (6.8%)). Eyes with varying starting conditions may benefit from surgery and experience visual improvement. Descemet membrane endothelial keratoplasty is an effective treatment for a variety of endothelial disorders in the eyes. Further long-term studies are needed.