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Outcome and risk factors of vitreoretinal surgery in pediatric patients with familial exudative vitreoretinopathy

Graefe's Archive for Clinical and Experimental Ophthalmology May 13, 2020

El-Khoury S, Clement A, Chehaibou I, et al. - Researchers conducted this retrospective interventional case series to assess the outcome for vitreoretinal surgery in children with familial exudative vitreoretinopathy (FEVR) and to evaluate the risk factors correlated with failure. The sample consisted of 43 consecutive eyes (34 patients) with vitreoretinal surgery for FEVR. Ocular status prior to intervention and at last follow-up and all surgical steps have been recorded. Surgery was successful in 30 eyes (70%) and failed in 13 eyes (30%) after a mean follow-up of 3.3 ± 3.4 years (median 2.3; 0.5–15.7 years). In Stages 2 and 3, eyes with tractional epiretinal membrane tend to benefit from vitrectomy and membrane peeling with a positive risk-benefit profile. Advanced stages have poor success rate and minimal functional progress, but surgery appears effective in selected cases.

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