Sultan P, et al. - Researchers compared oral vs intravenous iron therapy to treat postpartum anemia by performing a systematic review of randomized trials. The inclusion criteria was met by 15 randomized trials (n=1,001 and 1,181 women receiving oral iron and intravenous iron, respectively). Women who received intravenous iron displayed almost 1 g/dL higher hemoglobin concentrations at 6 weeks postpartum when compared to those receiving oral iron. Further, intravenous iron also displayed a reassuring safety profile. Oral iron use had weaker hemoglobin response and a higher risk of gastrointestinal side-effects. These findings suggest that consideration should be given to intravenous iron as a viable treatment option for postpartum iron deficiency anemia.