Passarelli MN, Mott LA, Barry EL, et al. - By conducting a secondary analysis of 4 randomized clinical trials, researchers investigated the association between antibiotics use and the risk of new colorectal adenomas among people with prior adenomas. Participants mentioned all currently employed prescription drugs shortly following an initial colorectal adenoma diagnosis and 2 or 3 times a year thereafter over 3 to 5 years of follow-up. Overall, a total of 5,174 participants (3,491 men and 1,683 women) were enrolled in the 4 trials. Among these, {greater than or equal to}1 follow-up colonoscopy was completed by 4,769 (92%). Use of oral antibiotics on {greater than or equal to}2 occasions was admitted by 763 (15%) participants. Findings demonstrated that use of oral antibiotics during colonoscopic surveillance following an initial adenoma diagnosis was not related to the risk of these polyps.