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Optic disc and peripapillary vessel density measured with optical coherence tomography angiography and its associations in Chinese adults: A large population-based study

British Journal of Ophthalmology May 28, 2021

Zhu MM, Choy BNK, You QS, et al. - In this population-based cross-sectional eye survey, researchers sought to examine the optic disc and peripapillary vessel density, as well as its ocular and systemic associations, in healthy eyes among adult Chinese population. This investigation was carried out on Chinese adults residing in Hong Kong. The sample consisted of 1,891 participants (1,891 eyes) who completed 4.5×4.5 mm optical coherence tomography angiography scans. Four hundred four of the 1,891 eyes were excluded due to poor scan quality, optic disc or retinal disorders, or non-Chinese ethnicity. This large population-based cross-sectional study provided quantitative data on the optic disc and peripapillary nerve fibre layer plexus (NFLP) vessel density (VD) which can serve as a normative reference for clinical use. In addition to age, gender, and AL, the scan signal strength should be considered when evaluating NFLP VD.

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