Eskola M, et al. - Researchers assessed the impacts of intermittent modalities of renal replacement therapy (IRRT) on outcomes of acute kidney injury (AKI) patients both in intensive care units (ICUs) and non-ICU dialysis units. They studied patient and RRT characteristics as well as outcomes at 90 days, 1 year, and 3 years for ICU and non-ICU patients (total n = 138; 65 ICU, 73 non-ICU) requiring RRT for AKI and chosen to receive IRRT. Based on the evaluation of 3-year kidney function and mortality, they found that IRRT provided dismal outcome when adopted as a treatment option for AKI patients. Although pre-existing chronic kidney disease (CKD) was identified as a major risk factor for end-stage renal disease after AKI, patients without prior CKD also had poor kidney survival.