Wang S, et al. - Among 130 consecutive patients with a confirmed diagnosis of hypertrophic obstructive cardiomyopathy (HOCM), researchers assessed the link between nonsustained ventricular tachycardia (NSVT) and obstructive sleep apnea (OSA). All patients underwent polysomnography and Holter electrocardiography. OSA was present in 72 (55.4%), including 38 with mild, 21 with moderate, and 13 with severe OSA, and 27 patients (20.8%) had NSVT. Findings revealed that, as the severity of OSA increased, an accompanying increase in the prevalence of NSVT was evident (none, mild, moderate, and severe: 12.1%, 15.8%, 33.3%, and 53.8%, respectively). Among the different OSA groups, a significantly higher apnea-hypopnea index was observed in patients with NSVT vs those without NSVT. After adjustment for age, sex, and body mass index in multivariate logistic regression analysis, the only factors that showed association with NSVT included family history of hypertrophic cardiomyopathy or sudden cardiac death and apnea-hypopnea index. Overall, in patients with HOCM, an independent association of the presence and severity of OSA with NSVT (a risk factor for sudden cardiac death and cardiovascular death in HOCM patients) was demonstrated.