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Nucleated cell count has negligible predictive value for the number of colony- forming units for connective tissue progenitor cells (stem cells) in bone marrow aspirate harvested from the proximal humerus during arthroscopic rotator cuff repair

Arthroscopy Feb 13, 2021

Muench LN, Berthold DP, Kia C, et al. - Researchers examined if nucleated cell count (NCC) could serve as an approximation for the number of colony-forming units (CFUs) in concentrated bone marrow aspirate (cBMA) retrieved from the proximal humerus. They harvested bone marrow aspirate (BMA) from the proximal humerus in 96 patients (mean age: 56.2±7.0 years) during arthroscopic rotator cuff repair. Concentrated BMA was identified containing a mean of 26.3 ± 6.8 × 10 6 nucleated cells per cc, which yielded a mean of 1,421.7 ± 802.7 CFUs in cell culture. Findings revealed negligible predictive value NCC for the total number of CFUs for connective tissue progenitor cells in bone marrow aspirate obtained from the proximal humerus during arthroscopic rotator cuff repair.

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