Yang J, et al. - In view of the growing immunocompromised population in China, researchers reviewed healthcare workers for issues connected to nosocomial transmission and the seroprevalence rate of varicella zoster virus (VZV). For nosocomial transmission of chickenpox, they conducted retrospective case finding based on clinical features consistent with chickenpox. Findings suggest a repeated occurrence of nosocomial transmission of VZV in the hospital setting. Worryingly, seronegativity for VZV was observed in 11.6% of healthcare workers (HCWs), which could raise the risk of nosocomial infection and outbreak for other vulnerable co-workers and patients. In a teaching hospital, this is particularly noteworthy, as many immunocompromised patients are managed in this environment. This study displayed a lower positive predictive value of self-reported varicella on the seroprevalence rate vs those reported in other countries. This emphasizes considering serological testing of VZV antibodies with ensuing vaccination for all non-immune HCWs.