Scott GD, et al. - This study aspired to formulate clinically relevant normative flow cytometry data for understudied benign lymph nodes and to characterize outliers. Normative ranges were yielded by the diagnostic immunophenotyping data from benign lymph nodes for clinical use. Outliers raising suspicion for B or T cell lymphoma did not appear to be infrequent (26% of benign lymph nodes). Hence, there was a necessity for proceeding with caution when interpreting outliers in the absence of excisional biopsy or clinical history, particularly in patients with concomitant immunosuppression or inflammatory disease.