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Nonalcoholic fatty liver disease in the Rotterdam Study: About muscle mass, sarcopenia, fat mass, and fat distribution

Journal of Bone and Mineral Research Jun 21, 2019

Alferink LJM, et al. - In an elderly population-based study, researchers assessed body composition and muscle function on their impact on nonalcoholic fatty liver disease (NAFLD), defined as liver steatosis in absence of secondary causes for steatosis. The study sample consisted of 4,609 participants of European descent who went through dual-energy X-ray absorptiometry and hepatic ultrasonography; 1,623 of these had NAFLD. According to findings, normal-weight NAFLD was found to be linked with both high-fat mass and low skeletal muscle index. However, as evaluated by android-fat-to-gynoid-fat ratio, prevalence of NAFLD was best predicted by fat distribution.

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