Kwok CS, et al. - Researchers assessed 30-day unplanned readmissions after an admission with a primary discharge diagnosis of non-specific chest pain. Study participants included patients with a primary diagnosis of non-specific chest pain in the Nationwide Readmission Database who were admitted between 2010 and 2014. A diagnosis of non-specific chest pain was noted in a total of 1,842,270 patients, with the 30-day unplanned readmission rate of 8.6%. From 2010 to 2014, 30-day unplanned readmissions increased from 8.1% to 9.5%. Most 30-day unplanned readmissions were for non-cardiac reasons (73.4%); the three most prevalent being neuropsychiatric (10.9%), gastrointestinal (10.5%), and infections (9.9%). The three most prevalent cardiac causes were related to coronary artery disease, including angina (8.4%), arrhythmias (6.6%), and heart failure 5.5%. Alcohol misuse, renal failure, cancer, discharge to a nursing home, and discharge against medical advice were the strongest predictors of readmission. Fewer unplanned readmissions were noted among patients who received a cardiovascular investigation vs those who did not receive any test.