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Non-idiopathic peripheral facial palsy: Prognostic factors for outcome

European Archives of Oto-Rhino-Laryngology Oct 11, 2020

Geißler K, Urban E, Volk GF, et al. - In the absence of data on patients’ and diagnostic factors for prognostication of complete recovery in patients with non-idiopathic peripheral facial palsy (FP), researchers sought to analyze the recovery rates for the different causes and identified prognostic factors of complete recovery. Cohort register-based study of 264 individuals with non-idiopathic peripheral FP and uniform diagnostics and standardized treatment in a university hospital from 2007 to 2017. Clinical data, facial grading, electrodiagnostics, motor function tests, non-motor function tests, and the onset of prednisolone therapy have been evaluated for their effect on the probability of complete recovery utilizing univariable and multivariable statistics. A reactivation of Varicella Zoster Virus (VZV; 36.4%) was the most frequent reason for a non-idiopathic peripheral FP. Non-idiopathic FP infectious causes such as VZV reactivation and Lyme disease had the best probability for complete recovery. A worse prognosis was for post-surgery FP.

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