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Nocturnal blood pressure rise as a predictor of cognitive impairment among the elderly: A retrospective cohort study

BMC Geriatrics Aug 18, 2021

Xing Y, Sun Y, Wang S, et al. - Ambulatory blood pressure (BP) monitoring (ABPM)-based BP control is very important for prevention of cognitive dysfunction progression in elderly.

  • 305 elderly participants aged ≥65 years participated.

  • A dipper pattern, nocturnal BP rise, and a non-dipper pattern was detected in 13.1%, 45.6%, and 41.3%, respectively, using ABPM.

  • A greater cognitive impairment (CI) was seen in those elderly patients who experienced nocturnal BP rise.

  • CI significantly elevated all-cause mortality in the elderly, but the nocturnal BP rise did not.

  • 35 all-cause deaths and 33 cases of major adverse cardiac and cerebrovascular events were revealed after 2.03 years of follow-up.

  • All-cause mortality in elderly was not significantly predicted by nocturnal BP rise.

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