Rüdiger R, et al. - This study was intended to report the evaluation on the treatment response rate and cancer survival in German patients with and without an immigrant background that were treated at our comprehensive cancer center in Germany. Between April 2002 and December 2015, researchers considered 8,162 cancer patients treated at the Center for Integrated Oncology, University Hospital Bonn, Germany for matched-pair analysis. A sum of 422 patients (n = 211, Germans with migration background; n = 211, native German population) were screened to compare for the treatment response and survival rates (i.e., 5-year overall survival, progression-free survival, and time to progression) using these stringent criteria. No significant differences were found in cancer survival between German patients with an immigrant background and native German patients. However, at our comprehensive cancer center, the advanced treatment protocols implemented may possibly account for the low variance in outcome. To perform similar studies with a broader perspective, they offer that certain risk factors (country-of-origin-specific infections, dietary habits, epigenetics for chronic diseases etc.) should be considered, particularly in the further trials that will recruit new arrivals from the 2015 German refugee crisis.