Maher MA, et al. - In this prospective randomized study, researchers studied the tocolytic action of nifedipine in combination with sildenafil citrate (SC) and assessed the efficacy this combination vs nifedipine alone for inhibiting threatened preterm labor (PTL). From January 2015 to November 2016, 239 women with threatened PTL received either nifedipine with SC or nifedipine alone. Nifedipine combined with SC was associated with fewer deliveries within 7 days of admission, prolonged latency, fewer admissions to neonatal intensive care unit, fewer very preterm deliveries and increased neonatal birth weight. Hence, for tocolytic therapy during threatened preterm labor, vaginal SC combined with nifedipine proved to be an effective option.