Karamchandani K, Pyati S, Bryan W, et al. - In this study, researchers measured new persistent opioid use in patients discharged following postoperative intensive care within the Veterans Health Administration and reported variations over time and values prior to and following 2013, when both the initiation of the Veterans Health Administration Opioid Safety Initiative and release of pain, agitation, and delirium guidelines for patients with critical illness happened. New persistent opioid use was recently defined as the most prevalent postoperative complication following surgery in the United States. However, less is known about the extent to which this an issue happens following ICU care, a setting where opioid use is usual and considerable proportions of patients receive opioid prescriptions at discharge. Persistent opioid use may be a part of the postintensive care syndrome, a syndrome of cognitive, psychiatric, and/or physical disability following treatment in an ICU.