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Neuropsychiatric outcome in subgroups of Intensive Care Unit survivors: Implications for after-care

Journal of Critical Care Nov 21, 2019

Dijkstra-Kersten SMA, Kok L, Kerckhoffs MC, et al. - Researchers undertook this single-center cohort study, to compare different subgroups of Intensive Care Unit (ICU) survivors in terms of anxiety, depression, and post-traumatic stress disorder (PTSD) symptoms and health-related quality of life (HrQoL). This inquiry was held in a mixed-ICU in the Netherlands, and included 1,730 survivors of an ICU admission ≥ 48 h. One year post-discharge, a survey was conducted among survivors, including the Hospital Anxiety and Depression Scale (HADS), Impact of Event Scale (IES/IES-R), and EQ-5D (response rate of 67%). They found that 34%, 33%, and 19% of ICU survivors stated symptoms of anxiety (HADS anxiety ≥ 8), depression (HADS depression ≥ 8), and PTSD (IES ≥ 35; IES-R ≥ 1.6), respectively, as well as a median HrQoL utility score of 0.81. For participants who had survived Acute Respiratory Distress Syndrome, sepsis, severe multiple organ failure (SOFA > 11), or ICU stay ≥ 7 days, these values remained similar. Based on these findings, experts inferred that prevention and treatment for neuropsychiatric symptoms in ICU survivors are significant in general, not only in particular patient groups.
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