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Neurological sequelae remain frequent after bacterial meningitis in children

Acta Pediatrica Jul 25, 2019

Svendsen MB, et al. - Using modified Poisson regression, researchers investigated the incidence, clinical presentation and risk factors for neurological sequelae after childhood community-acquired bacterial meningitis (CABM). Participants in the study were all children (aged 1 month to 15 years old) with CABM in North Denmark Region, 1998-2016. In 86 patients with a median age of 1.4 years, 88 cases of CABM were identified. The most common pathogen was Neisseria meningitidis. There were 27% in whom neurological sequelae occurred, including hearing deficits (15%), cognitive impairment (12%), and paresis or sensory deficits (9%). There were unfavorable outcomes in 18% of patients and 3% died. The only independent risk factor for developing neurological sequelae was abnormalities on cranial imaging in adjusted analysis.

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