Fan G, Dai F, Chen S, et al. - This research was sought to ascertain the clinical characteristics of this neurological involvement in patients with primary Sjögren’s syndrome (pSS). Between January 2015 and June 2017, researchers studied the clinical data of 205 patients with pSS who were admitted to the department. They compared characteristics and laboratory findings of pSS patients with neurological abnormalities with pSS patients without. In patients with pSS, neurological involvement is common and needs to be carefully assessed. The results considered that individuals with pSS with a high titer of anti-Sjögren’s syndrome type A and low presence of anti-SSB antibodies might have a relatively high risk of developing neurological involvement. Future trials should focus on distinguishing biomarkers that may aid in the early diagnosis of neurological involvement in patients with pSS.