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Negative predictors of shunt surgery outcome in normal pressure hydrocephalus

Acta Neurologica Scandinavica Feb 03, 2020

Bådagård H, et al. - Among 332 patients with idiopathic normal pressure hydrocephalus (iNPH; characterized by progressive balance and gait disturbances, cognitive dysfunction, and urinary incontinence), researchers examined the impact of high age and vascular comorbidity on outcome after shunt surgery. They consecutively involved patients who were treated with shunts between 2011 and 2015 at a single centre. To examine the predictive effects of age and vascular comorbidity on shunt surgery outcomes, a multivariable model was used. With age, both the incidence of iNPH and vascular comorbidity rises. After shunt surgery, increased age and established cerebrovascular disease were associated with less favorable outcomes. Shunt surgery can still help patients with iNPH and high age or a history of stroke, but these factors should be weighed when choosing patients for shunt surgery. Long waiting period for shunt surgery has been a poor outcome indicator, which means that iNPH is a progressive neurological disorder with symptoms deteriorating over time. Shunt surgery should not be delayed after diagnosis has been established.
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