Stearns D, et al. - In view of the observation that unintentional non-fire-related (UNFR) carbon monoxide (CO) poisoning is a leading cause of poisoning in the US and a preventable cause of death, national estimates of accidental CO poisoning were generated and the populations most at risk were characterized. Researchers analyzed UNFR CO poisoning cases using hospitalization and Emergency Department (ED) data from the Healthcare Costs and Utilization Project National Inpatient Sample and Nationwide Emergency Department databases and noted a decline in ED visits over the study period. However, the data suggested no change in hospitalization rates. This emphasizes the need for prevention efforts, such as education in the ED setting, increased use of CO alarms, and proper use and maintenance of fuel-powered household appliances. Patients who were older (aged 45–64 years), white, male, or living in the South or Midwest comprised most of the UNFR CO hospital cases.