Nasopharyngeal isolates and their clinical impact on young children with asthma: A pilot study
Journal of Asthma and Allergy Sep 20, 2018
Alsuwaidi AR, et al. - From December 2016 to March 2017, researchers collected 50 nasopharyngeal specimens from 18 patients (age, 5.0±1.1 years) with asthma and 9 specimens from 9 control children (age, 4.9±1.0 years) in order to assess the nasopharyngeal colonization in children with asthma and to determine the prevalence of pathogens and their contribution to respiratory symptoms and airway resistance during winter. In both groups (patients and controls), Streptococcus pneumoniae, Haemophilus influenzae, and rhinovirus were the most commonly isolated organisms. Isolation of multiple respiratory pathogens from many patients with asthma seems to suggest their contribution to disease symptoms and airway resistance. This emphasizes the benefits of minimization of children’s exposure to respiratory pathogens, especially during winter.
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