Johnson EG, Nguyen J, Oyler D, et al. - By performing this single center retrospective cohort review, researchers compared total perioperative opioid use in patients treated with naloxone continuous infusion (NCI) for the prevention of spinal cord ischemia, vs those not receiving NCI, in endovascular aortic repair. Participants included patients receiving elective thoracic, thoracoabdominal or abdominal aortic endovascular repair. Depending on the use of NCI as a component of a spinal protection protocol, experts separated patients. Opioid needs, in milligram morphine equivalents, during the first 48 hours or during NCI was assessed as the primary endpoint. As per findings, greater quantities of opioids were needed as well as higher postoperative pain was experienced in patients receiving NCI to prevent spinal cord ischemia vs those not requiring naloxone.