Kang HM, Park KC, Park J, et al. - Researchers aimed at determining the genetic characteristics linked with eradication failure of Staphylococcus aureus in infants below 90 days old. They prospectively obtained S. aureus isolated from clinical specimen cultures (blood, surgical tissue, or drainage, pus, etc.) and routine screening cultures in the neonatal intensive care unit (nasal and axillary skin swab) from patients below 90 days old for 1 year, from August 2017 to July 2018. During the study period, inclusion was performed of 40 nonduplicate isolates for analyses, of which 70.0% were methicillin-resistant S. aureus (MRSA). The nasal carriages of preterm infants were identified as having mupirocin, chlorhexidine, and quaternary ammonium compound (QAC)-resistant MRSAs harboring the Panton-Valentine leukocidin (PVL) toxin gene. One-fourth of the isolates from this highly vulnerable patient population, was identified harboring mupirocin-resistant genes, and all were resistant to QAC disinfectants. These strains are associated with persistence in both carriage and environmental reservoirs within the hospitals.