Lunski MJ, Burton J, Tawagi K, et al. - Researchers evaluated coronavirus disease 2019 death rates among patients suffering from cancer compared with those without cancer and investigated possible statistically significant features contributing to mortality, in this largest and only multivariate study in the United States. In this retrospective analysis, patients older than 18 years were eligible. This study involved 312 patients with cancer and 4,833 patients without cancer. An increased mortality in the setting of infection with severe acute respiratory syndrome coronavirus 2 was observed in patients with cancer vs patients without cancer. The greatest risk of death was observed in patients with cancer who were 65 years of age or older and those with certain comorbidities. Male gender, a history of chronic kidney disease, and obesity were other significant risk factors for raised mortality. Seemingly, recent cancer‐directed therapy and disease status also play roles in mortality.