Maccora S, Bolognini N, Cosentino G, et al. - As assessment of susceptibility to crossmodal illusions such as the Sound-Induced Flash Illusion (SIFI) can provide information regarding multisensory processing and patients with episodic migraine show reduced SIFI (ie fission illusion), especially during the attack, researchers investigated their hypothesis that chronic migraine patients should consistently report less illusory effects than healthy controls and if drugs intake also affects SIFI. On such a basis, 63 chronic migraine (CM) patients, including 52 patients with Medication Overuse Headache (MOH), were compared with 24 healthy controls regarding the proneness to SIFI. Relative to controls, all migraine patients exhibited decreased fission phenomena. they identified significantly less fission effects among triptan MOH patients (n = 23) than other chronic migraine groups (p = 0.008). Outcomes thus suggest the association of CM – both with and without medication overuse – with a higher visual cortical responsiveness which causes deficit of multisensorial processing, as assessed by the SIFI.