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Multiple reflex pathways contribute to bladder activation by intraurethral stimulation in persons with spinal cord injury

Urology Sep 19, 2017

McGee MJ, et al. - The physicians conducted this work to assess the urodynamic impacts of electrical co-stimulation of 2 individual sites in the proximal and distal urethra in persons with spinal cord injury (SCI). The results showed that pudendal nerve afferents are a promising target to restore lost bladder control, as stimulation with different frequencies may be applied to treat urinary incontinence and increase continent volumes or to generate stimulation-evoked bladder contractions for on-demand voiding. This work distinguished that co-stimulation of multiple afferent reflex pathways can improve activation of spinal circuits and may enable improved bladder emptying in spinal cord injury when stimulation of a single pathway is not sufficient.
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