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Multicenter study of the relationship between carbapenem MIC values and clinical outcome of patients with Acinetobacter bacteremia

Antimicrobial Agents and Chemotherapy Sep 02, 2017

Yang YS, et al. - Different recommendations offered by Clinical and Laboratory Standards Institute (CLSI) and the European Committee on Antimicrobial Susceptibility Testing (EUCAST) for carbapenem MIC susceptibility breakpoints for Acinetobacter species led researchers to conduct this work to determine the optimal predictive breakpoints based on the survival of patients with Acinetobacter bacteremia treated with a carbapenem. Findings revealed that patients treated with a carbapenem had a more favorable outcome when the carbapenem MICs of their isolates were ≤4 mg/liter than those with MICs of ≥8 mg/liter.
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