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MRI‐defined sarcopenia predicts mortality in patients with chronic liver disease

Liver International Nov 03, 2020

Beer L, Bastati N, Ba‐Ssalamah A, et al. - This retrospective single‐centre study was undertaken to determine if sarcopenia, diagnosed by an abbreviated magnetic resonance imaging (MRI) protocol is a risk factor for hepatic decompensation and mortality in patients with chronic liver disease (CLD). The sample consisted of 265 patients (164 men, mean age 54 ± 16 years) with CLD who had undergone MRI of the liver between 2010 and 2015. On unenhanced and contrast‐enhanced T1‐weighted and T2‐weighted axial images, transverse psoas muscle thickness (TPMT) was measured. The inter‐observer agreement for the TPMT measurements, as well as the intra‐observer agreement between the three image sequences were outstanding. Without the need for contrast injection, sarcopenia can be easily assessed by a short MRI exam. Sarcopenia, particularly in patients with compensated‐advanced CLD, is a risk factor for mortality.

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