Rey MV, et al. - In this study, researchers assessed the occurrence of movement disorders (MDs) in depressive patients exposed to antipsychotic drugs (APDs) vs nonexposed depressive patients and APD-treated schizophrenic patients by recruiting 452 depressive patients not exposed to APDs (group A), 156 depressive patients exposed to APDs (group B), and 75 patients with schizophrenia on APDs (group C). Findings suggested MDs in depression were independently and significantly linked to male sex, use first-generation APDs, and lithium exposure. In depressive patients, use of these drugs should be cautious.