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Mortality in young adult patients with acute ischaemic stroke

Acta Neurologica Scandinavica Jan 08, 2020

Schneider S, et al. - Among young patients (aged 18 to 54-year) with ischaemic stroke, researchers discovered short-and long-term mortality, clinical determinants, and causes of death. This hospital-based study was conducted in the two largest hospitals in Estonia from 2003 to 2012. In order to identify determinants of mortality, Logistic regression and Cox proportional hazard models with backwards stepwise analysis have been used. Seven hundred thirty-eight patients were identified, of whom 124 died during the 5-year follow-up. Data reported that cumulative mortality rates were 4.5% and 16.8%, respectively, at 30 days and 5 years. It was noted that the proportion of deaths from vascular causes was 87.9% at 1 month and 54.6% at 5 years. Findings suggested an independent association of 30-day mortality with severe stroke, with a National Institutes of Health Stroke Scale (NIHSS) score > 15, and post-stroke infections. Post-stroke infections, structural cardiac diseases, and moderate stroke severity with NIHSS score of 7-15 were the determinants of 5-year mortality. Such findings highlight the need in such patient groups for more successful preventive approaches.
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