Jeyaraman K, et al. – In this study, researchers assessed mortality outcomes in Australian patients with diabetic foot ulcers (DFU), a common problem in longstanding diabetes. Between January 2003 and June 2015, they included all patients with DFU presenting for the first time to the Multi-Disciplinary Foot Clinic (MDFC) at Royal Darwin Hospital, Northern Territory Australia. Of the 666 individuals evaluated, 513 were included in the final analysis. The median follow-up period was 5.8 years; the mean age of participants at inclusion was 59.9 ± 12.3 years and 62.8% were males. A full 93.6% had type 2 diabetes and the median diabetes duration was 7 years. A total of 199 deaths were reported, with a 5-year mortality rate of 24.6% and a 10-year mortality rate of 45.4%. According to findings, patients with DFU have high mortality, and age, chronic kidney disease, and low levels of albumin increase this risk. Chronic kidney disease (24.6%), cardiovascular events (19.6%), sepsis (15.6%), respiratory failure (10.0%), malignancy (9.5%), and multi-organ failure (5.0%) were the most common causes of death. The investigators recommended interventions that concentrate on ulcer prevention and reduction of aggressive risk factors.